Juvenile Acanthosis Nigricans and Insulin Resistance

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Acanthosis nigricans: a flag for insulin resistance

Objectives: Acanthosis nigricans refers to the velvety, black hyperpigmentation seen in the flexures. It is a cutaneous marker for insulin resistance (IR), some metabolic disorders and rarely malignancy. When secondary to IR, it is asymptomatic, except for the hyperpigmentation. The neck is the most accessible and easiest to grade. Our aim was to identify the predictive value of the grades of a...

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Acanthosis nigricans and insulin resistance in overweight children and adolescents.

BACKGROUND Studies have suggested an association between the presence of acanthosis nigricans (AN) and the development of diabetes. OBJECTIVE To investigate the association between AN and insulin resistance (IR) in overweight children and adolescents receiving care at the Center for Childhood Obesity, Campina Grande, PB. METHODS This cross-sectional study was conducted between April 2009 an...

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Association of acanthosis nigricans and skin tags with insulin resistance.

Insulin resistance is a metabolic disorder in which target cells fail to respond to normal levels of circulating insulin. Insulin resistance has been associated with presence of acanthosis nigricans and acrochordons. It is known that early diagnosis and early initial treatment are of paramount importance to prevent a series of future complications. These dermatoses may represent an easily ident...

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Comparison of Insulin resistance in obese women with and without Acanthosis Nigricans

Background and aim: Acanthosis nigricans (AN) is characterized by hyperpigmented velvety plaques of body folds and neck. Insulin can have a role in the pathogenesis of this disease and hyperinsulinemia as a consequence of insulin resistance may stimulate the formation of the characteristic plaques of AN. In this study insulin resistance was compared in obese women with and without AN.</sp...

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ژورنال

عنوان ژورنال: Pediatric Dermatology

سال: 2002

ISSN: 0736-8046,1525-1470

DOI: 10.1046/j.1525-1470.2002.00013.x